BDBM50084723 3-(Hydroxy-p-tolyl-methyl)-1-methyl-4-p-tolyl-piperidin-4-ol::CHEMBL333476

SMILES CN1CCC(O)(C(C1)[C@@H](O)c1ccc(C)cc1)c1ccc(C)cc1

InChI Key InChIKey=LWMFMZKTEROARR-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50084723   

TargetSodium-dependent dopamine transporter(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50084723(3-(Hydroxy-p-tolyl-methyl)-1-methyl-4-p-tolyl-pipe...)
Affinity DataKi:  1.07E+4nMAssay Description:Binding Affinity to cocaine site of dopamine transporter in caudate nuclei which was homogenized and incubated with [3H]mazindol. More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50084723(3-(Hydroxy-p-tolyl-methyl)-1-methyl-4-p-tolyl-pipe...)
Affinity DataKi:  1.58E+4nMAssay Description:Inhibition of [3H]DA Uptake at dopamine transporter in rat cortex was measured by liquid scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed