BDBM50084361 4-[3-(4-Fluoro-phenyl)-2-oxo-2,3-dihydro-oxazol-4-yl]-benzenesulfonamide::CHEMBL70921

SMILES NS(=O)(=O)c1ccc(cc1)-c1coc(=O)n1-c1ccc(F)cc1

InChI Key InChIKey=GHHGHECKSJIOSV-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50084361   

TargetProstaglandin G/H synthase 1(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50084361(4-[3-(4-Fluoro-phenyl)-2-oxo-2,3-dihydro-oxazol-4-...)
Affinity DataIC50: 1.32E+4nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50084361(4-[3-(4-Fluoro-phenyl)-2-oxo-2,3-dihydro-oxazol-4-...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50084361(4-[3-(4-Fluoro-phenyl)-2-oxo-2,3-dihydro-oxazol-4-...)
Affinity DataIC50: 1.50E+3nMAssay Description:Binding affinity towards Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50084361(4-[3-(4-Fluoro-phenyl)-2-oxo-2,3-dihydro-oxazol-4-...)
Affinity DataIC50: 1.32E+4nMAssay Description:Binding affinity towards Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50084361(4-[3-(4-Fluoro-phenyl)-2-oxo-2,3-dihydro-oxazol-4-...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of COX-2 in LPS-stimulated human whole blood after 24 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed