BDBM50084239 CHEMBL125626::N,N-Diethyl-4-(morpholin-4-yl-phenyl-methyl)-benzamide

SMILES CCN(CC)C(=O)c1ccc(cc1)C(N1CCOCC1)c1ccccc1

InChI Key InChIKey=HXDJHYKSRHALMQ-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50084239   

TargetDelta-type opioid receptor(Human)
Astrazeneca R&D Montreal

Curated by ChEMBL
LigandPNGBDBM50084239(N,N-Diethyl-4-(morpholin-4-yl-phenyl-methyl)-benza...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity against human opioid receptor delta 1 using [125I]-[D-Ala2]-deltorphin II as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50084239(N,N-Diethyl-4-(morpholin-4-yl-phenyl-methyl)-benza...)
Affinity DataKi:  3.00E+3nMAssay Description:In vitro radioligand binding assay, for inhibition of [3H]DADLE (Tyr-D-Ala-Gly-Phe-D-Leu) binding to Opioid receptor delta 1, in rat brain membranes ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50084239(N,N-Diethyl-4-(morpholin-4-yl-phenyl-methyl)-benza...)
Affinity DataKi:  1.00E+4nMAssay Description:In vitro radioligand binding assay, for inhibition of [3H]U-69593 binding to Opioid receptor kappa 1, in guinea pig brain membranes, at highest conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50084239(N,N-Diethyl-4-(morpholin-4-yl-phenyl-methyl)-benza...)
Affinity DataKi:  1.00E+4nMAssay Description:In vitro radioligand binding assay, for inhibition of [3H]DAMGO (Tyr-D-Ala-Gly-(Me)-Phe-Gly-ol) binding to Opioid receptor mu 1 in rat brain membrane...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2012
Entry Details Article
PubMed