BDBM50084227 2-(diethylamino)-5-methyl-4-oxo-4H-thieno[2,3-d][1,3]oxazine-6-carboxamide::2-Diethylamino-5-methyl-4-oxo-4H-thieno[2,3-d][1,3]oxazine-6-carboxylic acid amide::CHEMBL153784

SMILES CCN(CC)c1nc2sc(C(N)=O)c(C)c2c(=O)o1

InChI Key InChIKey=IBNVKZPFJZTZCA-UHFFFAOYSA-N

Data  2 KI  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50084227   

TargetNeutrophil elastase(Human)
University of Leipzig

Curated by ChEMBL
LigandPNGBDBM50084227(2-Diethylamino-5-methyl-4-oxo-4H-thieno[2,3-d][1,3...)
Affinity DataKd:  620nMAssay Description:Inhibitory activity against human leukocyte elastaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50084227(2-Diethylamino-5-methyl-4-oxo-4H-thieno[2,3-d][1,3...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibitory activity AChE from Electrophorus electricus using ATCh substrate and DTNB by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
University of Leipzig

Curated by ChEMBL
LigandPNGBDBM50084227(2-Diethylamino-5-methyl-4-oxo-4H-thieno[2,3-d][1,3...)
Affinity DataKi:  91nMAssay Description:Inhibitory activity against human leukocyte elastaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBile salt-activated lipase(Bovine)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50084227(2-Diethylamino-5-methyl-4-oxo-4H-thieno[2,3-d][1,3...)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibitory activity against bovine pancreatic CEase in presence of pNPB chromogenic substrate by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed