BDBM50084106 CHEMBL77513::Sodium; [(1S,3S)-1-hydroxy-3-((E)-3-hydroxy-7-phenyl-hept-1-enyl)-cyclohexyl]-acetate

SMILES OC(CCCCc1ccccc1)\C=C\[C@H]1CCC[C@@](O)(CC([O-])=O)C1

InChI Key InChIKey=HGDRLKMEWSBKRS-UHFFFAOYSA-M

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50084106   

TargetLeukotriene B4 receptor 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50084106(Sodium; [(1S,3S)-1-hydroxy-3-((E)-3-hydroxy-7-phen...)
Affinity DataIC50: 800nMAssay Description:Compound was evaluated for inhibitory activity against LTB4 receptor in human neutrophil membranes using [3H]- LTB4 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetLeukotriene B4 receptor 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50084106(Sodium; [(1S,3S)-1-hydroxy-3-((E)-3-hydroxy-7-phen...)
Affinity DataIC50: 7.00E+4nMAssay Description:Compound was evaluated for inhibitory activity against LTB4 receptor in human neutrophil membranes using [3H]- LTB4 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetLeukotriene B4 receptor 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50084106(Sodium; [(1S,3S)-1-hydroxy-3-((E)-3-hydroxy-7-phen...)
Affinity DataIC50: 800nMAssay Description:Compound was evaluated for inhibitory activity against LTB4 receptor in human neutrophil membranes using [3H]- LTB4 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetLeukotriene B4 receptor 2(Human)
Cnrs 5074

Curated by ChEMBL
LigandPNGBDBM50084106(Sodium; [(1S,3S)-1-hydroxy-3-((E)-3-hydroxy-7-phen...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of binding of [3H]LTB4 (1 nM) to intact human polymorphonuclear leukocytes (PMNs)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 2(Human)
Cnrs 5074

Curated by ChEMBL
LigandPNGBDBM50084106(Sodium; [(1S,3S)-1-hydroxy-3-((E)-3-hydroxy-7-phen...)
Affinity DataIC50: 800nMAssay Description:Inhibition of binding of [3H]LTB4 (1 nM) to intact human polymorphonuclear leukocytes (PMNs)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed