BDBM50083610 1,9-dihydroxy-6-(2-hydroxy-1-hydroxymethylethylamino)-13-(3,4,5-trihydroxy-6-hydroxymethyltetrahydro-2H-2-pyranyl)-6,7,12,13-tetrahydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7-dione::CHEMBL322712

SMILES OCC(CO)NN1C(=O)c2c(C1=O)c1c3cccc(O)c3n(C3OC(CO)C(O)C(O)C3O)c1c1[nH]c3ccc(O)cc3c21

InChI Key InChIKey=RTYCLPBRMSOKKH-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50083610   

TargetDNA topoisomerase 2-binding protein 1(Human)
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50083610(1,9-dihydroxy-6-(2-hydroxy-1-hydroxymethylethylami...)
Affinity DataEC50: >5.00E+4nMAssay Description:In vitro inhibition of Topoisomerase II-mediated DNA cleavage using supercoiled pBR322 plasmid DNA.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 1(Human)
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50083610(1,9-dihydroxy-6-(2-hydroxy-1-hydroxymethylethylami...)
Affinity DataEC50:  510nMAssay Description:In vitro inhibition of Topoisomerase I-mediated DNA cleavage using supercoiled pBR322 plasmid DNA.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetO94806/P05129/P05771/P17252/P24723/P41743/Q02156/Q04759/Q05513/Q05655/Q15139(Human)
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50083610(1,9-dihydroxy-6-(2-hydroxy-1-hydroxymethylethylami...)
Affinity DataIC50: 2.00E+5nMAssay Description:In vitro inhibition of PKC mediated DNA cleavage.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed