BDBM50083600 2,10-dihydroxy-6-(2-hydroxy-1-hydroxymethylethylamino)-12-(3,4,5-trihydroxy-6-hydroxymethyltetrahydro-2H-2-pyranyl)-6,7,12,13-tetrahydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7-dione::CHEMBL112235

SMILES OCC(CO)NN1C(=O)c2c(C1=O)c1c3ccc(O)cc3n(C3OC(CO)C(O)C(O)C3O)c1c1[nH]c3cc(O)ccc3c21

InChI Key InChIKey=QMVPQBFHUJZJCS-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50083600   

TargetDNA topoisomerase 1(Human)
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50083600(2,10-dihydroxy-6-(2-hydroxy-1-hydroxymethylethylam...)
Affinity DataEC50:  51nMAssay Description:In vitro inhibition of Topoisomerase I-mediated DNA cleavage using supercoiled pBR322 plasmid DNA.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 2-binding protein 1(Human)
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50083600(2,10-dihydroxy-6-(2-hydroxy-1-hydroxymethylethylam...)
Affinity DataEC50: >5.00E+4nMAssay Description:In vitro inhibition of Topoisomerase II-mediated DNA cleavage using supercoiled pBR322 plasmid DNA.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetO94806/P05129/P05771/P17252/P24723/P41743/Q02156/Q04759/Q05513/Q05655/Q15139(Human)
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50083600(2,10-dihydroxy-6-(2-hydroxy-1-hydroxymethylethylam...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibition of PKC mediated DNA cleavage.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed