BDBM50083443 (4-Chloro-phenylamino)-[1-(3H-imidazol-4-ylmethyl)-7-phenyl-1,2,3,5-tetrahydro-benzo[e][1,4]diazepin-4-yl]-methyl-cyanamide::CHEMBL148811

SMILES Clc1ccc(NC(=NC#N)N2CCN(Cc3cnc[nH]3)c3ccc(cc3C2)-c2ccccc2)cc1

InChI Key InChIKey=NNDIRMVXWQCVQO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50083443   

TargetDimer of Protein farnesyltransferase subunit beta(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50083443((4-Chloro-phenylamino)-[1-(3H-imidazol-4-ylmethyl)...)
Affinity DataIC50: 1.42E+6nMAssay Description:Inhibitory activity against human purified recombinant farnesyltransferase (hFT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed