BDBM50083431 CHEMBL121010::[7-Bromo-1-(3H-imidazol-4-ylmethyl)-1,2,3,5-tetrahydro-benzo[e][1,4]diazepin-4-yl]-naphthalen-1-yl-methanone

SMILES Brc1ccc2N(Cc3cnc[nH]3)CCN(Cc2c1)C(=O)c1cccc2ccccc12

InChI Key InChIKey=AFGGHSFDNGPAOO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50083431   

TargetDimer of Protein farnesyltransferase subunit beta(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50083431([7-Bromo-1-(3H-imidazol-4-ylmethyl)-1,2,3,5-tetrah...)
Affinity DataIC50: 2.28E+5nMAssay Description:Inhibitory activity against human purified recombinant farnesyltransferase (hFT)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50083431([7-Bromo-1-(3H-imidazol-4-ylmethyl)-1,2,3,5-tetrah...)
Affinity DataIC50: 228nMAssay Description:Inhibition of purified recombinant human farnesyltransferase (FT)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed