BDBM50083414 1-[1-(3H-Imidazol-4-ylmethyl)-7-phenyl-1,2,3,5-tetrahydro-benzo[e][1,4]diazepin-4-yl]-2-(4-methoxy-phenyl)-ethane-1,2-dione::CHEMBL348452

SMILES COc1ccc(cc1)C(=O)C(=O)N1CCN(Cc2cnc[nH]2)c2ccc(cc2C1)-c1ccccc1

InChI Key InChIKey=JATKYKJLTLNLNE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50083414   

TargetDimer of Protein farnesyltransferase subunit beta(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50083414(1-[1-(3H-Imidazol-4-ylmethyl)-7-phenyl-1,2,3,5-tet...)
Affinity DataIC50: 9.10E+4nMAssay Description:Inhibitory activity against human purified recombinant farnesyltransferase (hFT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed