BDBM50083215 (+/-)-3-(4-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-piperazin-1-yl)-1-phenyl-propan-1-ol::3-(4-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-piperazin-1-yl)-1-phenyl-propan-1-ol::CHEMBL152928::CHEMBL417660

SMILES OC(CCN1CCN(CCOC(c2ccc(F)cc2)c2ccc(F)cc2)CC1)c1ccccc1

InChI Key InChIKey=FRNMVZXBCHKPGE-UHFFFAOYSA-N

Data  8 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50083215   

TargetSodium-dependent serotonin transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50083215(CHEMBL152928 | CHEMBL417660 | 3-(4-{2-[Bis-(4-fluo...)
Affinity DataIC50: 69nMAssay Description:Reuptake inhibition of [3H]-5-HT (5-HT) in rat.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50083215(CHEMBL152928 | CHEMBL417660 | 3-(4-{2-[Bis-(4-fluo...)
Affinity DataIC50: 5.57nMAssay Description:Reuptake inhibition of [3H]-labeled dopamine (DA) in rat.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50083215(CHEMBL152928 | CHEMBL417660 | 3-(4-{2-[Bis-(4-fluo...)
Affinity DataKi:  2.10nMAssay Description:Binding affinity for dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50083215(CHEMBL152928 | CHEMBL417660 | 3-(4-{2-[Bis-(4-fluo...)
Affinity DataKi:  2.10nMAssay Description:Binding affinity towards dopamine transporter (DAT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50083215(CHEMBL152928 | CHEMBL417660 | 3-(4-{2-[Bis-(4-fluo...)
Affinity DataKi:  2.10nMAssay Description:Binding affinity for dopamine transporter (DAT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50083215(CHEMBL152928 | CHEMBL417660 | 3-(4-{2-[Bis-(4-fluo...)
Affinity DataKi:  2.14nMAssay Description:Binding affinity against dopamine transporter labelled with [125I]- RTI-55 in rat.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50083215(CHEMBL152928 | CHEMBL417660 | 3-(4-{2-[Bis-(4-fluo...)
Affinity DataKi:  117nMAssay Description:Binding affinity against Serotonin transporter (SERT) labelled with [125I]RTI-55 in rat.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50083215(CHEMBL152928 | CHEMBL417660 | 3-(4-{2-[Bis-(4-fluo...)
Affinity DataKi:  117nMAssay Description:Binding affinity for serotonin transporter (SERT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50083215(CHEMBL152928 | CHEMBL417660 | 3-(4-{2-[Bis-(4-fluo...)
Affinity DataKi:  120nMAssay Description:Binding affinity for serotonin transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50083215(CHEMBL152928 | CHEMBL417660 | 3-(4-{2-[Bis-(4-fluo...)
Affinity DataKi:  120nMAssay Description:Binding affinity towards rat serotonin transporter (SERT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed