BDBM50083200 1-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-4-[(E)-3-(4-methoxy-phenyl)-allyl]-piperazine::1-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-4-[3-(4-methoxy-phenyl)-allyl]-piperazine::CHEMBL43124

SMILES COc1ccc(\C=C\CN2CCN(CCOC(c3ccc(F)cc3)c3ccc(F)cc3)CC2)cc1

InChI Key InChIKey=SUPURMVBOPJGOE-UHFFFAOYSA-N

Data  2 KI  2 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50083200   

TargetSodium-dependent serotonin transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50083200(1-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-4-[(E)...)
Affinity DataIC50: 392nMAssay Description:Reuptake inhibition of [3H]-5-HT (5-HT) in rat.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50083200(1-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-4-[(E)...)
Affinity DataIC50: 9.80nMAssay Description:Reuptake inhibition of [3H]-labeled dopamine (DA) in rat.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50083200(1-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-4-[(E)...)
Affinity DataKd:  65nMAssay Description:Inhibition of radioligand [125I]RTI-55 binding to human Dopamine transporter in clonal cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50083200(1-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-4-[(E)...)
Affinity DataKd:  372nMAssay Description:Inhibition of [125I]RTI-55 binding to human SERT in clonal cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50083200(1-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-4-[(E)...)
Affinity DataKi:  15.1nMAssay Description:Binding affinity against dopamine transporter labelled with [125I]- RTI-55 in rat.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50083200(1-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-4-[(E)...)
Affinity DataKi:  90nMAssay Description:Binding affinity against Serotonin transporter (SERT) labelled with [125I]RTI-55 in rat.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed