BDBM50082921 6-[(Diphenylamino)-methyl]-pteridine-2,4-diamine::CHEMBL424113

SMILES Nc1nc(N)c2nc(CN(c3ccccc3)c3ccccc3)cnc2n1

InChI Key InChIKey=WVNIWFAZVBLXHS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50082921   

TargetDihydrofolate reductase(Rat)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50082921(6-[(Diphenylamino)-methyl]-pteridine-2,4-diamine |...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibitory activity against DHFR (Dihydrofolate reductase) from Rat liverMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDihydrofolate reductase(Mycobacterium avium)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50082921(6-[(Diphenylamino)-methyl]-pteridine-2,4-diamine |...)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibitory activity against DHFR (Dihydrofolate reductase) from Mycobacterium aviumMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50082921(6-[(Diphenylamino)-methyl]-pteridine-2,4-diamine |...)
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibitory activity against DHFR (Dihydrofolate reductase) from Pneumocystis carinii.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50082921(6-[(Diphenylamino)-methyl]-pteridine-2,4-diamine |...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibitory activity against DHFR (Dihydrofolate reductase) from Toxoplasma gondii.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed