BDBM50081704 5-Methoxy-3-((R)-1-methyl-pyrrolidin-2-ylmethyl)-1H-indole::CHEMBL137485

SMILES COc1ccc2[nH]cc(C[C@H]3CCCN3C)c2c1

InChI Key InChIKey=MKEGUJPBCIXABO-UHFFFAOYSA-N

Data  1 KI  6 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50081704   

Target5-hydroxytryptamine receptor 1B(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50081704(5-Methoxy-3-((R)-1-methyl-pyrrolidin-2-ylmethyl)-1...)
Affinity DataIC50: 830nMAssay Description:Binding affinity against 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1D(Guinea pig)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50081704(5-Methoxy-3-((R)-1-methyl-pyrrolidin-2-ylmethyl)-1...)
Affinity DataEC50:  43nMAssay Description:Effect on forskolin stimulated adenylate cyclase activity at 5-HT1D receptor of guinea pig substantia nigra.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50081704(5-Methoxy-3-((R)-1-methyl-pyrrolidin-2-ylmethyl)-1...)
Affinity DataIC50: 33nMAssay Description:Binding affinity against 5-hydroxytryptamine 1C receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50081704(5-Methoxy-3-((R)-1-methyl-pyrrolidin-2-ylmethyl)-1...)
Affinity DataEC50:  35nMAssay Description:Effect on forskolin stimulated adenylate cyclase activity at 5-hydroxytryptamine 1A receptor of guinea pig hippocampus.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50081704(5-Methoxy-3-((R)-1-methyl-pyrrolidin-2-ylmethyl)-1...)
Affinity DataIC50: 17nMAssay Description:Binding affinity against 5-hydroxytryptamine 2 receptor using [125I]DOI as radioligand.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50081704(5-Methoxy-3-((R)-1-methyl-pyrrolidin-2-ylmethyl)-1...)
Affinity DataIC50: 730nMAssay Description:Binding affinity against 5-hydroxytryptamine 2 receptor using [3H]ket as radioligand.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1D(Guinea pig)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50081704(5-Methoxy-3-((R)-1-methyl-pyrrolidin-2-ylmethyl)-1...)
Affinity DataIC50: 24nMAssay Description:Binding affinity against 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50081704(5-Methoxy-3-((R)-1-methyl-pyrrolidin-2-ylmethyl)-1...)
Affinity DataIC50: 10nMAssay Description:Binding affinity against 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50081704(5-Methoxy-3-((R)-1-methyl-pyrrolidin-2-ylmethyl)-1...)
Affinity DataKi:  400nMAssay Description:Compound was tested for binding affinity using [3H]MDL-100,907 at 5-hydroxytryptamine 2A receptor sites in rat cortical homogenate.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed