BDBM50081702 5-Methoxy-3-((S)-1-methyl-pyrrolidin-2-ylmethyl)-1H-indole::CHEMBL133939

SMILES COc1ccc2[nH]cc(C[C@@H]3CCCN3C)c2c1

InChI Key InChIKey=MKEGUJPBCIXABO-UHFFFAOYSA-N

Data  1 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50081702   

Target5-hydroxytryptamine receptor 1B(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50081702(5-Methoxy-3-((S)-1-methyl-pyrrolidin-2-ylmethyl)-1...)
Affinity DataIC50: 5.80E+3nMAssay Description:Binding affinity against 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50081702(5-Methoxy-3-((S)-1-methyl-pyrrolidin-2-ylmethyl)-1...)
Affinity DataIC50: 1.20E+3nMAssay Description:Binding affinity against 5-hydroxytryptamine 1C receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50081702(5-Methoxy-3-((S)-1-methyl-pyrrolidin-2-ylmethyl)-1...)
Affinity DataIC50: 140nMAssay Description:Effect on forskolin stimulated adenylate cyclase activity at 5-hydroxytryptamine 1A receptor of guinea pig hippocampus.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Guinea pig)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50081702(5-Methoxy-3-((S)-1-methyl-pyrrolidin-2-ylmethyl)-1...)
Affinity DataIC50: 420nMAssay Description:Binding affinity against 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50081702(5-Methoxy-3-((S)-1-methyl-pyrrolidin-2-ylmethyl)-1...)
Affinity DataIC50: 8.40E+3nMAssay Description:Binding affinity against 5-hydroxytryptamine 2 receptor using [3H]ket as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50081702(5-Methoxy-3-((S)-1-methyl-pyrrolidin-2-ylmethyl)-1...)
Affinity DataIC50: 680nMAssay Description:Binding affinity against 5-hydroxytryptamine 2 receptor using [125I]DOI as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50081702(5-Methoxy-3-((S)-1-methyl-pyrrolidin-2-ylmethyl)-1...)
Affinity DataKi: >9.40E+3nMAssay Description:Compound was tested for binding affinity using [3H]MDL-100,907 at 5-hydroxytryptamine 2A receptor sites in rat cortical homogenate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed