BDBM50081520 3-[(S)-3-(5-Chloro-thieno[3,2-b]pyridine-2-sulfonylamino)-2-oxo-pyrrolidin-1-ylmethyl]-benzamidine::CHEMBL90741

SMILES NC(=N)c1cccc(CN2CC[C@H](NS(=O)(=O)c3cc4nc(Cl)ccc4s3)C2=O)c1

InChI Key InChIKey=VWOKJHQJMHGXMV-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50081520   

TargetCoagulation factor X(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50081520(3-[(S)-3-(5-Chloro-thieno[3,2-b]pyridine-2-sulfony...)
Affinity DataKi:  31nMAssay Description:Binding affinity against serine protease factor Xa (fXa)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50081520(3-[(S)-3-(5-Chloro-thieno[3,2-b]pyridine-2-sulfony...)
Affinity DataKi: >2.90E+3nMAssay Description:Binding affinity against trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50081520(3-[(S)-3-(5-Chloro-thieno[3,2-b]pyridine-2-sulfony...)
Affinity DataKi:  3.10E+3nMAssay Description:Binding affinity against thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50081520(3-[(S)-3-(5-Chloro-thieno[3,2-b]pyridine-2-sulfony...)
Affinity DataKi:  5.80E+3nMAssay Description:Binding affinity against plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50081520(3-[(S)-3-(5-Chloro-thieno[3,2-b]pyridine-2-sulfony...)
Affinity DataKi: >8.70E+3nMAssay Description:Binding affinity against tissue plasminogen activator (t-Pa)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVitamin K-dependent protein C(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50081520(3-[(S)-3-(5-Chloro-thieno[3,2-b]pyridine-2-sulfony...)
Affinity DataKi: >1.80E+4nMAssay Description:Binding affinity against activated protein C (APC)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed