BDBM50079856 CHEMBL108721::[2,6-Dibromo-4-(6-bromo-benzo[b]naphtho[2,3-d]thiophen-11-yl)-phenoxy]-acetic acid

SMILES OC(=O)COc1c(Br)cc(cc1Br)-c1c2c(sc3ccccc23)c(Br)c2ccccc12

InChI Key InChIKey=BOOMNQMMZXXWGF-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50079856   

TargetReceptor-type tyrosine-protein phosphatase beta(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50079856([2,6-Dibromo-4-(6-bromo-benzo[b]naphtho[2,3-d]thio...)
Affinity DataIC50: 600nMAssay Description:The compound was tested in vitro for the inhibitory activity against Protein-tyrosine phosphatase beta (SH-PTP1) (human PTPases.)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50079856([2,6-Dibromo-4-(6-bromo-benzo[b]naphtho[2,3-d]thio...)
Affinity DataIC50: 390nMAssay Description:The compound was tested in vitro for the inhibitory activity against Protein-tyrosine phosphatase 1B (human PTPases.)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50079856([2,6-Dibromo-4-(6-bromo-benzo[b]naphtho[2,3-d]thio...)
Affinity DataIC50: 386nMAssay Description:The compound was tested in vitro for the inhibitory activity against Protein-tyrosine phosphatase 1B (human PTPases.)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50079856([2,6-Dibromo-4-(6-bromo-benzo[b]naphtho[2,3-d]thio...)
Affinity DataIC50: 1.70E+4nMAssay Description:The compound was tested in vitro for the inhibitory activity against Protein-tyrosine phosphatase 1 alpha (LRP) (human PTPases.)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase F(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50079856([2,6-Dibromo-4-(6-bromo-benzo[b]naphtho[2,3-d]thio...)
Affinity DataIC50: 1.50E+3nMAssay Description:The compound was tested in vitro for the inhibitory activity against LAR (human Protein-tyrosine phosphatase F)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50079856([2,6-Dibromo-4-(6-bromo-benzo[b]naphtho[2,3-d]thio...)
Affinity DataIC50: 5.00E+3nMAssay Description:The compound was tested in vitro for the inhibitory activity against Protein-tyrosine phosphatase 1C (SH-PTP1) (human PTPases.)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase C(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50079856([2,6-Dibromo-4-(6-bromo-benzo[b]naphtho[2,3-d]thio...)
Affinity DataIC50: 9.10E+3nMAssay Description:The compound was tested in vitro for the inhibitory activity against CD45 antigen (human PTPases.)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 3(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50079856([2,6-Dibromo-4-(6-bromo-benzo[b]naphtho[2,3-d]thio...)
Affinity DataIC50: 7.90E+3nMAssay Description:The compound was tested in vitro for the inhibitory activity against Dual specificity protein phosphatase 3 (SH-PTP1) (human PTPases.)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 12(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50079856([2,6-Dibromo-4-(6-bromo-benzo[b]naphtho[2,3-d]thio...)
Affinity DataIC50: 2.30E+3nMAssay Description:The compound was tested in vitro for the inhibitory activity against Protein tyrosine phosphatase PEST (SH-PTP1) (human PTPases.)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed