BDBM50079677 (S)-2-[3-({[3-(4-Cyano-benzyl)-3H-imidazol-4-ylmethyl]-amino}-methyl)-benzoylamino]-4-methylsulfanyl-butyric acid methyl ester::CHEMBL61594

SMILES COC(=O)[C@H](CCSC)NC(=O)c1cccc(CNCc2cncn2Cc2ccc(cc2)C#N)c1

InChI Key InChIKey=ZREJJLKRRAAESU-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50079677   

TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Human)
Merck Research Laboratories

Curated by ChEMBL

LigandBDBM50079677((S)-2-[3-({[3-(4-Cyano-benzyl)-3H-imidazol-4-ylmet...)Copy SMILESCopy InChI

Affinity DataIC50: 260nMAssay Description:Reduction in the FTase-catalyzed (enzyme purified from bovine brain) incorporation of [3H]-FPP into recombinant Ha-Ras.More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
11/10/2009
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