BDBM50079676 (S)-2-(3-{[Benzyl-(1H-imidazol-4-ylmethyl)-amino]-methyl}-benzoylamino)-4-methylsulfanyl-butyric acid::CHEMBL61452

SMILES CSCC[C@H](NC(=O)c1cccc(CN(Cc2cnc[nH]2)Cc2ccccc2)c1)C(O)=O

InChI Key InChIKey=QADTXPJGMQLBEN-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50079676   

TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Human)
Merck Research Laboratories

Curated by ChEMBL

LigandBDBM50079676((S)-2-(3-{[Benzyl-(1H-imidazol-4-ylmethyl)-amino]-...)Copy SMILESCopy InChI

Affinity DataIC50: 255nMAssay Description:Reduction in the FTase-catalyzed (enzyme purified from bovine brain) incorporation of [3H]-FPP into recombinant Ha-Ras.More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
11/10/2009
Entry Details Article
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