BDBM50079664 (S)-2-(3-{[(4-Cyano-benzyl)-(3H-imidazol-4-ylmethyl)-amino]-methyl}-benzoylamino)-4-methylsulfanyl-butyric acid::CHEMBL292568
SMILES CSCC[C@H](NC(=O)c1cccc(CN(Cc2cnc[nH]2)Cc2ccc(cc2)C#N)c1)C(O)=O
InChI Key InChIKey=PMOBHNORZCLDTE-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50079664
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Human)
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of [3H]FPP incorporation into recombinant Ha-Ras by bovine brain farnesyltransferaseMore data for this Ligand-Target Pair
TargetGeranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha(Human)
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of geranylgeranyl transferase I (GGTase-I)More data for this Ligand-Target Pair