BDBM50079659 (S)-2-(3-{[Benzoyl-(1H-imidazol-4-ylmethyl)-amino]-methyl}-benzoylamino)-4-methylsulfanyl-butyric acid::CHEMBL294200

SMILES CSCC[C@H](NC(=O)c1cccc(CN(Cc2cnc[nH]2)C(=O)c2ccccc2)c1)C(O)=O

InChI Key InChIKey=FFPUVADUWGYOLM-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50079659   

TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Human)
Merck Research Laboratories

Curated by ChEMBL

LigandBDBM50079659((S)-2-(3-{[Benzoyl-(1H-imidazol-4-ylmethyl)-amino]...)Copy SMILESCopy InChI

Affinity DataIC50: 1.75E+3nMAssay Description:Reduction in the FTase-catalyzed (enzyme purified from bovine brain) incorporation of [3H]-FPP into recombinant Ha-Ras.More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
11/10/2009
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL