BDBM50079646 2-{5-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-1H-pyrrol-2-ylmethylene}-malononitrile::4-(4-Chloro-phenyl)-1-[5-(2,2-dicyano-vinyl)-1H-pyrrol-2-ylmethyl]-piperazin-1-ium::CHEMBL303538

SMILES Clc1ccc(cc1)N1CCN(Cc2ccc(C=C(C#N)C#N)[nH]2)CC1

InChI Key InChIKey=HEBQIUNCEBCMFD-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50079646   

TargetD(4) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50079646(4-(4-Chloro-phenyl)-1-[5-(2,2-dicyano-vinyl)-1H-py...)
Affinity DataKi:  9.55nMAssay Description:Ability to displace [3H]spiperone from dopamine receptor D4.4 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50079646(4-(4-Chloro-phenyl)-1-[5-(2,2-dicyano-vinyl)-1H-py...)
Affinity DataKi:  11nMAssay Description:Binding affinity of compound towards human cloned Dopamine receptor D4.4 expressed in CHO cells using [3H]spiperone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
UniversitäT Erlangen - NüRnberg

Curated by ChEMBL
LigandPNGBDBM50079646(4-(4-Chloro-phenyl)-1-[5-(2,2-dicyano-vinyl)-1H-py...)
Affinity DataKi:  3.10E+4nMAssay Description:Ability to displace [3H]spiperone from the cloned human D3 dopamine receptor stably expressed in Chinese hamster ovary (CHO) cells was determined.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Bovine)
UniversitäT Erlangen - NüRnberg

Curated by ChEMBL
LigandPNGBDBM50079646(4-(4-Chloro-phenyl)-1-[5-(2,2-dicyano-vinyl)-1H-py...)
Affinity DataKi:  3.95E+4nMAssay Description:Ability to displace D1 selective radioligand [3H]-SCH- 23390 in bovine striatal membrane preparations was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
UniversitäT Erlangen - NüRnberg

Curated by ChEMBL
LigandPNGBDBM50079646(4-(4-Chloro-phenyl)-1-[5-(2,2-dicyano-vinyl)-1H-py...)
Affinity DataKi:  4.85E+4nMAssay Description:Ability to displace [3H]spiperone from the cloned human Dopamine receptor D2S stably expressed in Chinese hamster ovary (CHO) cells was determined.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
UniversitäT Erlangen - NüRnberg

Curated by ChEMBL
LigandPNGBDBM50079646(4-(4-Chloro-phenyl)-1-[5-(2,2-dicyano-vinyl)-1H-py...)
Affinity DataKi:  5.90E+4nMAssay Description:Ability to displace [3H]spiperone from the cloned human Dopamine receptor D2S stably expressed in Chinese hamster ovary (CHO) cells was determined.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed