BDBM50079455 CHEMBL46486::tetramethylammonium

SMILES C[N+](C)(C)C

InChI Key InChIKey=QEMXHQIAXOOASZ-UHFFFAOYSA-N

Data  9 KI  4 IC50

PDB links: 11 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50079455   

TargetSolute carrier family 22 member 1(Rat)
Kyoto University Hospital

Curated by ChEMBL
LigandPNGBDBM50079455(CHEMBL46486 | tetramethylammonium)
Affinity DataIC50: 1.14E+6nMAssay Description:TP_TRANSPORTER: inhibition of TEA uptake (TEA: 50 uM) in OCT1-expressing MDCK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier family 22 member 2(Rat)
Kyoto University Hospital

Curated by ChEMBL
LigandPNGBDBM50079455(CHEMBL46486 | tetramethylammonium)
Affinity DataIC50: 1.67E+6nMAssay Description:TP_TRANSPORTER: inhibition of TEA uptake (TEA: 50 uM) in OCT2-expressing MDCK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier family 22 member 2(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50079455(CHEMBL46486 | tetramethylammonium)
Affinity DataIC50: 1.50E+5nMAssay Description:TP_TRANSPORTER: inhibition of MPP+ uptake (MPP+: 1 uM) in Xenopus laevis oocytesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier family 22 member 2(Rat)
Kyoto University Hospital

Curated by ChEMBL
LigandPNGBDBM50079455(CHEMBL46486 | tetramethylammonium)
Affinity DataIC50: 6.30E+5nMAssay Description:TP_TRANSPORTER: inhibition of TEA uptake (TEA: 10 uM) in Xenopus laevis oocytesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50079455(CHEMBL46486 | tetramethylammonium)
Affinity DataKi:  24nMAssay Description:Binding affinity at heteropentameric Nicotinic acetylcholine receptor alpha4-beta2 subtype using [3H]bungarotoxin as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50079455(CHEMBL46486 | tetramethylammonium)
Affinity DataKi:  2.30E+3nMAssay Description:Binding affinity at homopentameric Nicotinic acetylcholine receptor alpha-7 subtype using [3H]S-(-)-nicotine as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAlpha-bungarotoxin(Many-banded krait)
Mcgill University

Curated by PDSP Ki Database
LigandPNGBDBM50079455(CHEMBL46486 | tetramethylammonium)
Affinity DataKi:  2.40E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHigh affinity choline transporter 1(Mouse)
Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50079455(CHEMBL46486 | tetramethylammonium)
Affinity DataKi:  3.01E+4nMAssay Description:Inhibition of [3H]choline uptake at choline transporter 1 in mouse brain synaptosomeMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier family 22 member 1(Rat)
Kyoto University Hospital

Curated by ChEMBL
LigandPNGBDBM50079455(CHEMBL46486 | tetramethylammonium)
Affinity DataKi:  1.00E+6nMAssay Description:TP_TRANSPORTER: inhibition of TEA uptake in Xenopus laevis oocytesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier family 22 member 1(Rat)
Kyoto University Hospital

Curated by ChEMBL
LigandPNGBDBM50079455(CHEMBL46486 | tetramethylammonium)
Affinity DataKi:  9.05E+5nMAssay Description:TP_TRANSPORTER: inhibition of MPP+ uptake in Xenopus laevis oocytesMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetSolute carrier family 22 member 1(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50079455(CHEMBL46486 | tetramethylammonium)
Affinity DataKi:  1.24E+7nMAssay Description:TP_TRANSPORTER: inhibition of MPP+ uptake in Xenopus laevis oocytesMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetSolute carrier family 22 member 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50079455(CHEMBL46486 | tetramethylammonium)
Affinity DataKi:  2.04E+6nMAssay Description:TP_TRANSPORTER: inhibition of MPP+ uptake in Xenopus laevis oocytesMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetSolute carrier family 22 member 2(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50079455(CHEMBL46486 | tetramethylammonium)
Affinity DataKi:  1.80E+5nMAssay Description:TP_TRANSPORTER: inhibition of TEA uptake in Xenopus laevis oocytesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed