BDBM50079259 3-(3-Carbamimidoyl-phenyl)-4,5-dihydro-isoxazole-5-carboxylic acid (2'-sulfamoyl-biphenyl-4-yl)-amide; TFA::CHEMBL301729::CHEMBL92523

SMILES NC(=N)c1cccc(c1)C1=NOC(C1)C(=O)Nc1ccc(cc1)-c1ccccc1S(N)(=O)=O

InChI Key InChIKey=SZLKLAYGGJRRDH-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50079259   

TargetCoagulation factor X(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50079259(CHEMBL92523 | CHEMBL301729 | 3-(3-Carbamimidoyl-ph...)
Affinity DataKi:  7.20nMAssay Description:Binding affinity towards human purified Coagulation factor Xa (FXa)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor X(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50079259(CHEMBL92523 | CHEMBL301729 | 3-(3-Carbamimidoyl-ph...)
Affinity DataKi:  7.20nMAssay Description:Binding affinity against the coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50079259(CHEMBL92523 | CHEMBL301729 | 3-(3-Carbamimidoyl-ph...)
Affinity DataKi:  83nMAssay Description:Binding affinity towards trypsin obtained from human purified enzymesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50079259(CHEMBL92523 | CHEMBL301729 | 3-(3-Carbamimidoyl-ph...)
Affinity DataKi:  3.90E+3nMAssay Description:Binding affinity towards thrombin obtained from human purified enzymesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed