BDBM50078642 CHEMBL3415384

SMILES CCN[C@H]1CN(CCCO)S(=O)(=O)c2sc(cc12)S(N)(=O)=O

InChI Key InChIKey=WQSYAXSFXFVBTJ-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50078642   

TargetCarbonic anhydrase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50078642(CHEMBL3415384)
Affinity DataIC50: 165nMAssay Description:Inhibition of human carbonic anhydrase 2 assessed as reduction in enzyme activity incubated for 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/27/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50078642(CHEMBL3415384)
Affinity DataKd:  0.136nMAssay Description:Binding affinity to human carbonic anhydrase 2 incubated for 1 hr using labeled BODIPY558/568-acetazolamide as tracer by fluorescence polarization ti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/27/2016
Entry Details Article
PubMed