BDBM50078395 (S)-1-(2-Hydroxycarbamoyl-cyclohexanecarbonyl)-pyrrolidine-2-carboxylic acid ((S)-1-carbamoyl-ethyl)-amide::CHEMBL80368

SMILES C[C@H](NC(=O)[C@@H]1CCCN1C(=O)C1CCCCC1C(=O)NO)C(N)=O

InChI Key InChIKey=LOSBOHMHLCTYGM-UHFFFAOYSA-N

Data  18 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 18 hits for monomerid = 50078395   

TargetXaa-Pro aminopeptidase 2(Rat)
Pharmacia and Upjohn

Curated by ChEMBL
LigandPNGBDBM50078395((S)-1-(2-Hydroxycarbamoyl-cyclohexanecarbonyl)-pyr...)
Affinity DataIC50: 5.00E+6nMAssay Description:Activity against membrane bound rat aminopeptidase PMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytosol aminopeptidase(Human)
Pharmacia and Upjohn

Curated by ChEMBL
LigandPNGBDBM50078395((S)-1-(2-Hydroxycarbamoyl-cyclohexanecarbonyl)-pyr...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition against Leucyl aminopeptidase from pig kidney.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytosol aminopeptidase(Human)
Pharmacia and Upjohn

Curated by ChEMBL
LigandPNGBDBM50078395((S)-1-(2-Hydroxycarbamoyl-cyclohexanecarbonyl)-pyr...)
Affinity DataIC50: 2.20E+5nMAssay Description:Inhibition against Leucyl aminopeptidase from pig kidney.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetXaa-Pro dipeptidase(Human)
Pharmacia and Upjohn

Curated by ChEMBL
LigandPNGBDBM50078395((S)-1-(2-Hydroxycarbamoyl-cyclohexanecarbonyl)-pyr...)
Affinity DataIC50: 5.00E+7nMAssay Description:Inhibition against Prolidase from pig kidney.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetXaa-Pro aminopeptidase 2(Human)
Pharmacia and Upjohn

Curated by ChEMBL
LigandPNGBDBM50078395((S)-1-(2-Hydroxycarbamoyl-cyclohexanecarbonyl)-pyr...)
Affinity DataIC50: 5.00E+6nMAssay Description:Inhibition against membrane bound human aminopeptidase PMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetXaa-Pro aminopeptidase 2(Human)
Pharmacia and Upjohn

Curated by ChEMBL
LigandPNGBDBM50078395((S)-1-(2-Hydroxycarbamoyl-cyclohexanecarbonyl)-pyr...)
Affinity DataIC50: 5.00E+6nMAssay Description:Inhibition against membrane bound monkey aminopeptidase PMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetXaa-Pro aminopeptidase 2(Human)
Pharmacia and Upjohn

Curated by ChEMBL
LigandPNGBDBM50078395((S)-1-(2-Hydroxycarbamoyl-cyclohexanecarbonyl)-pyr...)
Affinity DataIC50: 4.80E+4nMAssay Description:Inhibition against membrane bound human aminopeptidase PMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetXaa-Pro aminopeptidase 2(Rat)
Pharmacia and Upjohn

Curated by ChEMBL
LigandPNGBDBM50078395((S)-1-(2-Hydroxycarbamoyl-cyclohexanecarbonyl)-pyr...)
Affinity DataIC50: 3.70E+4nMAssay Description:Activity against membrane bound rat aminopeptidase PMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetXaa-Pro aminopeptidase 1(Human)
Pharmacia and Upjohn

Curated by ChEMBL
LigandPNGBDBM50078395((S)-1-(2-Hydroxycarbamoyl-cyclohexanecarbonyl)-pyr...)
Affinity DataIC50: 3.00E+6nMAssay Description:Inhibition against cytosolic Aminopeptidase P from human heart.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetXaa-Pro aminopeptidase 2(Human)
Pharmacia and Upjohn

Curated by ChEMBL
LigandPNGBDBM50078395((S)-1-(2-Hydroxycarbamoyl-cyclohexanecarbonyl)-pyr...)
Affinity DataIC50: 5.00E+6nMAssay Description:Inhibition against membrane bound human aminopeptidase PMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetXaa-Pro aminopeptidase 2(Human)
Pharmacia and Upjohn

Curated by ChEMBL
LigandPNGBDBM50078395((S)-1-(2-Hydroxycarbamoyl-cyclohexanecarbonyl)-pyr...)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition against membrane bound monkey aminopeptidase PMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetXaa-Pro dipeptidase(Human)
Pharmacia and Upjohn

Curated by ChEMBL
LigandPNGBDBM50078395((S)-1-(2-Hydroxycarbamoyl-cyclohexanecarbonyl)-pyr...)
Affinity DataIC50: 5.00E+7nMAssay Description:Inhibition against Prolidase from pig kidney.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetXaa-Pro aminopeptidase 1(Human)
Pharmacia and Upjohn

Curated by ChEMBL
LigandPNGBDBM50078395((S)-1-(2-Hydroxycarbamoyl-cyclohexanecarbonyl)-pyr...)
Affinity DataIC50: 5.00E+6nMAssay Description:Inhibition against cytosolic Aminopeptidase P from human heart.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetXaa-Pro aminopeptidase 2(Human)
Pharmacia and Upjohn

Curated by ChEMBL
LigandPNGBDBM50078395((S)-1-(2-Hydroxycarbamoyl-cyclohexanecarbonyl)-pyr...)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition against membrane bound monkey aminopeptidase PMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetXaa-Pro aminopeptidase 2(Rat)
Pharmacia and Upjohn

Curated by ChEMBL
LigandPNGBDBM50078395((S)-1-(2-Hydroxycarbamoyl-cyclohexanecarbonyl)-pyr...)
Affinity DataIC50: 5.00E+6nMAssay Description:Activity against membrane bound rat aminopeptidase PMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetXaa-Pro dipeptidase(Human)
Pharmacia and Upjohn

Curated by ChEMBL
LigandPNGBDBM50078395((S)-1-(2-Hydroxycarbamoyl-cyclohexanecarbonyl)-pyr...)
Affinity DataIC50: 1.70E+6nMAssay Description:Inhibition against Prolidase from pig kidney.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytosol aminopeptidase(Human)
Pharmacia and Upjohn

Curated by ChEMBL
LigandPNGBDBM50078395((S)-1-(2-Hydroxycarbamoyl-cyclohexanecarbonyl)-pyr...)
Affinity DataIC50: 2.20E+5nMAssay Description:Inhibition against Leucyl aminopeptidase from pig kidney.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetXaa-Pro aminopeptidase 1(Human)
Pharmacia and Upjohn

Curated by ChEMBL
LigandPNGBDBM50078395((S)-1-(2-Hydroxycarbamoyl-cyclohexanecarbonyl)-pyr...)
Affinity DataIC50: 3.00E+6nMAssay Description:Inhibition against cytosolic Aminopeptidase P from human heart.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed