BDBM50078015 CHEMBL3417395

SMILES CCOc1ccccc1N\N=C1/C(C)=NN(C1=O)c1nc(cs1)-c1ccccc1

InChI Key InChIKey=KOCVKGYKBLJEPK-UHFFFAOYSA-N

Data  3 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50078015   

TargetApoptosis regulator BAX(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50078015(CHEMBL3417395)
Affinity DataEC50:  8.20E+3nMAssay Description:Activation of Bax in human HuH7 cells assessed as inhibition of mitochondrial accumulation of fluorescent probe Mitotracker Red after 12 to 72 hrs by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2016
Entry Details Article
PubMed
TargetApoptosis regulator BAX(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50078015(CHEMBL3417395)
Affinity DataIC50: 3.31E+3nMAssay Description:Displacement of FITC-labeled BIM SAHB from recombinant BAX (unknown origin) measured for 20 mins by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetApoptosis regulator BAX(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50078015(CHEMBL3417395)
Affinity DataKi:  1.10E+3nMAssay Description:Displacement of FITC-BIM from recombinant N-terminal GST-tagged human BAX expressed in Escherichia coli after 30 mins by fluorescence polarization as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2016
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50078015(CHEMBL3417395)
Affinity DataKi:  3.00E+3nMAssay Description:Displacement of FITC-BIM from recombinant human Bcl-2 expressed in Escherichia coli after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2016
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50078015(CHEMBL3417395)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of FITC-BIM from recombinant human Bcl-XL expressed in Escherichia coli after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2016
Entry Details Article
PubMed