BDBM50077604 7-Chloro-4-[2-(4-chloro-benzylamino)-ethoxy]-1,3-dihydro-indol-2-one::CHEMBL302000

SMILES Clc1ccc(CNCCOc2ccc(Cl)c3NC(=O)Cc23)cc1

InChI Key InChIKey=JPSMZWRPAFVXDX-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50077604   

TargetD(2) dopamine receptor(Rat)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50077604(7-Chloro-4-[2-(4-chloro-benzylamino)-ethoxy]-1,3-d...)
Affinity DataKi:  1.40nMAssay Description:In vitro high binding affinity towards Dopamine receptor D2 by the displacement of [3H]quinpirole radioligand in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50077604(7-Chloro-4-[2-(4-chloro-benzylamino)-ethoxy]-1,3-d...)
Affinity DataKi:  4.10nMAssay Description:In vitro low binding affinity towards Dopamine receptor D2 by the displacement of [3H]spiperone radioligand in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50077604(7-Chloro-4-[2-(4-chloro-benzylamino)-ethoxy]-1,3-d...)
Affinity DataKi:  1.90E+3nMAssay Description:In vitro binding affinity towards 5-hydroxytryptamine 1A receptor by the displacement of [3H]8-OH-DPAT radioligand in rat hippocampal homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed