BDBM50077589 1-[4-(2-Benzylamino-ethoxy)-1H-indol-3-yl]-2,2,2-trifluoro-ethanone::CHEMBL60783

SMILES FC(F)(F)C(=O)c1c[nH]c2cccc(OCCNCc3ccccc3)c12

InChI Key InChIKey=NQQDGDDHTBBKPN-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50077589   

TargetD(2) dopamine receptor(Rat)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50077589(1-[4-(2-Benzylamino-ethoxy)-1H-indol-3-yl]-2,2,2-t...)
Affinity DataKi:  3nMAssay Description:In vitro high binding affinity towards Dopamine receptor D2 by the displacement of [3H]quinpirole radioligand in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50077589(1-[4-(2-Benzylamino-ethoxy)-1H-indol-3-yl]-2,2,2-t...)
Affinity DataKi:  17nMAssay Description:In vitro low binding affinity towards Dopamine receptor D2 by the displacement of [3H]spiperone radioligand in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50077589(1-[4-(2-Benzylamino-ethoxy)-1H-indol-3-yl]-2,2,2-t...)
Affinity DataKi:  30nMAssay Description:The compound was tested for binding affinity on [3H]8-OH-DPAT as specific ligand on 5-hydroxytryptamine 1A receptor in rat hippocampusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed