BDBM50076905 3-(2-Bromo-4-isopropyl-phenyl)-7-diethylamino-5-methyl-3H-thiazolo[4,5-d]pyrimidine-2-thione::CHEMBL18029

SMILES CCN(CC)c1nc(C)nc2n(-c3ccc(cc3Br)C(C)C)c(=S)sc12

InChI Key InChIKey=DIWNELUZISLUSY-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50076905   

TargetCorticotropin-releasing factor receptor 1(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076905(3-(2-Bromo-4-isopropyl-phenyl)-7-diethylamino-5-me...)
Affinity DataKi:  4.10nMAssay Description:Binding affinity against human Corticotropin releasing factor receptor 1 expressed in HEK 293E cells using [125I]TYR-oCRHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076905(3-(2-Bromo-4-isopropyl-phenyl)-7-diethylamino-5-me...)
Affinity DataKi:  4.10nMAssay Description:Compound was tested for the binding affinity to human corticotropin releasing factor 1 (hCRF1) receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed