BDBM50076315 (4S,5S)-5-(4-Chloro-phenyl)-2,2,4-trimethyl-2,3,4,5-tetrahydro-1H-6-oxa-1-aza-chrysene::CHEMBL286822

SMILES C[C@H]1CC(C)(C)Nc2ccc3-c4ccccc4O[C@@H](c4ccc(Cl)cc4)c3c12

InChI Key InChIKey=PZQCNOKCBJYQHG-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50076315   

TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076315((4S,5S)-5-(4-Chloro-phenyl)-2,2,4-trimethyl-2,3,4,...)
Affinity DataEC50:  39nMAssay Description:Compound was tested for agonistic activity by cotransfection assay against human Progesterone receptor in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076315((4S,5S)-5-(4-Chloro-phenyl)-2,2,4-trimethyl-2,3,4,...)
Affinity DataKi:  10nMAssay Description:Compound was evaluated for its binding affinity against baculovirus expressed Progesterone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed