BDBM50076139 (S)-2-{4-[(1H-Imidazol-4-ylmethyl)-amino]-2-naphthalen-1-yl-benzoylamino}-4-methyl-pentanoic acid methyl ester::CHEMBL27518

SMILES COC(=O)[C@H](CC(C)C)NC(=O)c1ccc(NCc2cnc[nH]2)cc1-c1cccc2ccccc12

InChI Key InChIKey=TUQRZGWNDBXSNP-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50076139   

TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Mouse)
Yale University

Curated by ChEMBL

LigandBDBM50076139((S)-2-{4-[(1H-Imidazol-4-ylmethyl)-amino]-2-naphth...)Copy SMILESCopy InChI

Affinity DataIC50: 3.00E+4nMAssay Description:In vivo for inhibition of farnesylation based on the inhibition of H-Ras processing.More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
11/10/2009
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL