BDBM50075787 4-[3-(4-Bromo-2-propoxy-phenyl)-5-(4-chloro-phenyl)-1H-pyrrol-2-yl]-pyridine::CHEMBL160287

SMILES CCCOc1cc(Br)ccc1-c1cc([nH]c1-c1ccncc1)-c1ccc(Cl)cc1

InChI Key InChIKey=XDRUMTNYWFDQKD-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50075787   

TargetGlucagon receptor(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50075787(4-[3-(4-Bromo-2-propoxy-phenyl)-5-(4-chloro-phenyl...)
Affinity DataIC50: 830nMAssay Description:Binding affinity towards glucagon receptor determined by reduction in binding of 125 I-glucagon to the murine glucagon receptor (mGLUR) expressed on ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50075787(4-[3-(4-Bromo-2-propoxy-phenyl)-5-(4-chloro-phenyl...)
Affinity DataIC50: 4nMAssay Description:Binding affinity towards glucagon receptor determined by reduction in binding of [125I]glucagon to the human glucagon receptor (GGR) expressed on CHO...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50075787(4-[3-(4-Bromo-2-propoxy-phenyl)-5-(4-chloro-phenyl...)
Affinity DataIC50: 130nMAssay Description:Binding affinity towards glucagon receptor determined by reduction in binding of [125I]glucagon to the human glucagon receptor (GGR) expressed on CHO...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon receptor(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50075787(4-[3-(4-Bromo-2-propoxy-phenyl)-5-(4-chloro-phenyl...)
Affinity DataIC50: 49nMAssay Description:Binding affinity towards glucagon receptor determined by reduction in binding of [125I]glucagon to the murine glucagon receptor (GGR) expressed on CH...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed