BDBM50075474 CHEMBL3415352

SMILES COc1cc(cc(OC)c1OC)-c1nc(SCC#C)nc(NNC(N)=S)c1C#N

InChI Key InChIKey=QSJWHWXROPOHCT-UHFFFAOYSA-N

Data  8 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50075474   

TargetLysine-specific histone demethylase 1A(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50075474(CHEMBL3415352)
Affinity DataKd:  3.70E+3nMAssay Description:Binding affinity to recombinant LSD1(unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2016
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50075474(CHEMBL3415352)
Affinity DataIC50: 1.25E+6nMAssay Description:Inhibition of MAOB (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2016
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50075474(CHEMBL3415352)
Affinity DataIC50: 1.25E+6nMAssay Description:Inhibition of MAOA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2016
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50075474(CHEMBL3415352)
Affinity DataIC50: 650nMAssay Description:Inhibition of recombinant LSD1 (157 to 852) (unknown origin) transfected in Escherichia coli BL21(DE) by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2016
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50075474(CHEMBL3415352)
Affinity DataIC50: 650nMAssay Description:Inhibition of LSD1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2019
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50075474(CHEMBL3415352)
Affinity DataIC50: 650nMAssay Description:Inhibition of LSD1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2020
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50075474(CHEMBL3415352)
Affinity DataIC50: 650nMAssay Description:Inhibition of LSD1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50075474(CHEMBL3415352)
Affinity DataIC50: 650nMAssay Description:Inhibition of LSD1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2019
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50075474(CHEMBL3415352)
Affinity DataIC50: 650nMAssay Description:Inhibition of LSD1 (unknown origin) (157 to 852 residues) expressed in Escherichia coli BL21(DE) cells using H3K4me2 as substrate by horseradish pero...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed