BDBM50075418 1-(2-Ethoxy-benzyl)-4-(4-methoxy-phenyl)-2-oxo-1,2-dihydro-benzo[4,5]furo[3,2-b]pyridine-3-carboxylic acid::CHEMBL157827

SMILES CCOc1ccccc1Cn1c2c(oc3ccccc23)c(-c2ccc(OC)cc2)c(C(O)=O)c1=O

InChI Key InChIKey=WPRKCOQUOSJKQM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50075418   

TargetEndothelin receptor type B(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50075418(1-(2-Ethoxy-benzyl)-4-(4-methoxy-phenyl)-2-oxo-1,2...)
Affinity DataIC50: 1.30E+3nMAssay Description:Ability to displace [125I]endothelin-1 from endothelin B receptor in porcine kidney membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM50075418(1-(2-Ethoxy-benzyl)-4-(4-methoxy-phenyl)-2-oxo-1,2...)
Affinity DataIC50: 900nMAssay Description:Ability to displace [125I]endothelin-1 from endothelin A receptor in rat aorta membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed