BDBM50075414 1-Benzyl-2-oxo-4-phenyl-1,2-dihydro-benzo[4,5]furo[3,2-b]pyridine-3-carboxylic acid::CHEMBL158123

SMILES OC(=O)c1c(-c2ccccc2)c2oc3ccccc3c2n(Cc2ccccc2)c1=O

InChI Key InChIKey=SURMPYFSKJGCGG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50075414   

TargetEndothelin-1 receptor(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM50075414(1-Benzyl-2-oxo-4-phenyl-1,2-dihydro-benzo[4,5]furo...)
Affinity DataIC50: 1.00E+4nMAssay Description:Ability to displace [125I]endothelin-1 from endothelin A receptor in rat aorta membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50075414(1-Benzyl-2-oxo-4-phenyl-1,2-dihydro-benzo[4,5]furo...)
Affinity DataIC50: 1.00E+4nMAssay Description:Ability to displace [125I]endothelin-1 from endothelin B receptor in porcine kidney membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed