BDBM50074611 CHEMBL170876::[3-(3-Chloro-phenyl)-bicyclo[2.2.2]oct-2-ylmethyl]-dimethyl-amine

SMILES CN(C)CC1C2CCC(CC2)C1c1cccc(Cl)c1

InChI Key InChIKey=XAYGSYISSLIYTN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50074611   

TargetSodium-dependent dopamine transporter(Rat)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50074611([3-(3-Chloro-phenyl)-bicyclo[2.2.2]oct-2-ylmethyl]...)
Affinity DataIC50: 86nMAssay Description:Inhibitory binding activity against rat striatal tissue using [3H]WIN-35248 as the radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50074611([3-(3-Chloro-phenyl)-bicyclo[2.2.2]oct-2-ylmethyl]...)
Affinity DataIC50: 283nMAssay Description:Inhibition of dopamine uptake into rat striatal tissue, using [3H]- dopamine as the radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50074611([3-(3-Chloro-phenyl)-bicyclo[2.2.2]oct-2-ylmethyl]...)
Affinity DataIC50: 86nMAssay Description:Inhibitory binding activity against rat striatal tissue using [3H]WIN-35248 as the radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50074611([3-(3-Chloro-phenyl)-bicyclo[2.2.2]oct-2-ylmethyl]...)
Affinity DataIC50: 283nMAssay Description:Inhibition of dopamine uptake into rat striatal tissue, using [3H]- dopamine as the radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2012
Entry Details Article
PubMed