BDBM50074328 CHEMBL164585::Thiophene-3-carboxylic acid

SMILES OC(=O)c1ccsc1

InChI Key InChIKey=YNVOMSDITJMNET-UHFFFAOYSA-N

Data  1 KI  5 IC50  2 Kd

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50074328   

TargetD-aspartate oxidase(Human)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50074328(Thiophene-3-carboxylic acid | CHEMBL164585)
Affinity DataIC50: 1.00E+7nMAssay Description:Inhibition of human recombinant N-terminal His-tagged DDO expressed in Escherichia coli BL21(DE3) using D-aspartate as substrate by colorimetric assa...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD-amino-acid oxidase(Human)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50074328(Thiophene-3-carboxylic acid | CHEMBL164585)
Affinity DataIC50: 4.92E+4nMAssay Description:Inhibition of human recombinant N-terminal His-tagged DAO expressed in Escherichia coli BL21(DE3) using D-alanine as substrate by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD-amino-acid oxidase(Human)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50074328(Thiophene-3-carboxylic acid | CHEMBL164585)
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of human recombinant N-terminal His-tagged DAO expressed in Escherichia coli BL21(DE3) using D-serine as substrate by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine racemase(Human)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50074328(Thiophene-3-carboxylic acid | CHEMBL164585)
Affinity DataIC50: 8.21E+6nMAssay Description:Inhibition of human recombinant N-terminal His-tagged serine racemase expressed in Escherichia coli BL21(DE3) using L-serine as substrate after 10 mi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase Fyn(Human)
The Albert Einstein College of Medicine of Yeshiva University

Curated by ChEMBL
LigandPNGBDBM50074328(Thiophene-3-carboxylic acid | CHEMBL164585)
Affinity DataKd:  700nMAssay Description:Dissociation constant for binding to SH2 domain of Fyn protein kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
The Albert Einstein College of Medicine of Yeshiva University

Curated by ChEMBL
LigandPNGBDBM50074328(Thiophene-3-carboxylic acid | CHEMBL164585)
Affinity DataKd:  260nMAssay Description:Dissociation constant for binding to SH2 domain of p56 lck tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD-amino-acid oxidase(Human)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50074328(Thiophene-3-carboxylic acid | CHEMBL164585)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of human DAO using D-serine as substrate after 20 mins in presence of FADMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD-amino-acid oxidase(Human)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50074328(Thiophene-3-carboxylic acid | CHEMBL164585)
Affinity DataKi:  8.16E+3nMAssay Description:Inhibition of human recombinant N-terminal His-tagged DAO expressed in Escherichia coli BL21(DE3) using D-serine as substrate by Lineweaver-Burk plot...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed