BDBM50074004 1'-[2-(2-pyridyl)ethyl]spiro[3,4-dihydro-2H-chromene-2,4'-(hexahydropyridine)]-4-one::CHEMBL98167

SMILES O=C1CC2(CCN(CCc3ccccn3)CC2)Oc2ccccc12

InChI Key InChIKey=YFZDJBNVNRXEMA-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50074004   

TargetAlpha-1A adrenergic receptor(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50074004(1'-[2-(2-pyridyl)ethyl]spiro[3,4-dihydro-2H-chrome...)
Affinity DataKi:  793nMAssay Description:Ability to displace [125I]HEAT from cloned human Alpha-1A adrenergic receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50074004(1'-[2-(2-pyridyl)ethyl]spiro[3,4-dihydro-2H-chrome...)
Affinity DataKi:  1.29E+3nMAssay Description:Displacement of [125I]HEAT from human Alpha-1B adrenergic receptor expressed in LM cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1D adrenergic receptor(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50074004(1'-[2-(2-pyridyl)ethyl]spiro[3,4-dihydro-2H-chrome...)
Affinity DataKi:  1.52E+3nMAssay Description:Displacement of [125I]HEAT from human Alpha-1D adrenergic receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed