BDBM50074003 1'-[2-(1-naphthyl)ethyl]spiro[3,4-dihydro-1H-isochromene-3,4'-(hexahydropyridine)]-1-one::CHEMBL98168

SMILES O=C1OC2(CCN(CCc3cccc4ccccc34)CC2)Cc2ccccc12

InChI Key InChIKey=AROUGQIPMYQUEE-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50074003   

TargetAlpha-1A adrenergic receptor(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50074003(1'-[2-(1-naphthyl)ethyl]spiro[3,4-dihydro-1H-isoch...)
Affinity DataKi:  45nMAssay Description:Ability to displace [125I]HEAT from cloned human Alpha-1A adrenergic receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1D adrenergic receptor(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50074003(1'-[2-(1-naphthyl)ethyl]spiro[3,4-dihydro-1H-isoch...)
Affinity DataKi:  60nMAssay Description:Displacement of [125I]HEAT from human Alpha-1D adrenergic receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50074003(1'-[2-(1-naphthyl)ethyl]spiro[3,4-dihydro-1H-isoch...)
Affinity DataKi:  137nMAssay Description:Displacement of [125I]HEAT from human Alpha-1B adrenergic receptor expressed in LM cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed