BDBM50073869 CHEMBL289731::N-[6-(4-Ethyl-thiazol-2-ylsulfanyl)-1-oxo-indan-5-yl]-methanesulfonamide

SMILES CCc1csc(Sc2cc3C(=O)CCc3cc2NS(C)(=O)=O)n1

InChI Key InChIKey=FSLBQTAGYFUJKD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50073869   

TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50073869(N-[6-(4-Ethyl-thiazol-2-ylsulfanyl)-1-oxo-indan-5-...)
Affinity DataIC50: 49nMAssay Description:Inhibition of human Prostaglandin G/H synthase 2 expressed in CHO (chinese hamster ovary) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50073869(N-[6-(4-Ethyl-thiazol-2-ylsulfanyl)-1-oxo-indan-5-...)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 activity in U937 microsomal assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50073869(N-[6-(4-Ethyl-thiazol-2-ylsulfanyl)-1-oxo-indan-5-...)
Affinity DataIC50: 280nMAssay Description:Inhibition of purified recombinant human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed