BDBM50073328 (1S,2R,3S,4R,8R,9R)-4,5-Dibenzyl-9-benzyloxy-2,3-dihydroxy-5,7-diaza-tricyclo[6.2.2.0*1,7*]dodecan-6-one::CHEMBL120800

SMILES O[C@@H]1[C@H](O)[C@]23CC[C@H]([C@@H](C2)OCc2ccccc2)N3C(=O)N(Cc2ccccc2)[C@@H]1Cc1ccccc1

InChI Key InChIKey=BIHUCLWSIWMAEN-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50073328   

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073328((1S,2R,3S,4R,8R,9R)-4,5-Dibenzyl-9-benzyloxy-2,3-d...)
Affinity DataKi:  750nMAssay Description:Compound was tested for the inhibition of HIV-1 protease by assaying the cleavage of a fluorescent peptide using HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed