BDBM50073273 3,4-Dimethyl-7-[3-(4-phenyl-piperazin-1-yl)-propoxy]-chromen-2-one::CHEMBL120661

SMILES Cc1c(C)c(=O)oc2cc(OCCCN3CCN(CC3)c3ccccc3)ccc12

InChI Key InChIKey=LNAQGJPALKPMLJ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50073273   

Target5-hydroxytryptamine receptor 1A(Rat)
University of Vigo

Curated by ChEMBL
LigandPNGBDBM50073273(3,4-Dimethyl-7-[3-(4-phenyl-piperazin-1-yl)-propox...)
Affinity DataKi:  5.30nMAssay Description:Compound was measured for the inhibition of [3H]8-OH-DPAT binding to rat hippocampus membrane (5-HT1A receptor)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Vigo

Curated by ChEMBL
LigandPNGBDBM50073273(3,4-Dimethyl-7-[3-(4-phenyl-piperazin-1-yl)-propox...)
Affinity DataKi:  5.90nMAssay Description:Compound was measured for the binding affinity in homogenated mouse fibroblast (LTK) cells transfected with human Dopamine receptor D2A using [3H]rac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
University of Vigo

Curated by ChEMBL
LigandPNGBDBM50073273(3,4-Dimethyl-7-[3-(4-phenyl-piperazin-1-yl)-propox...)
Affinity DataKi:  45nMAssay Description:Compound was measured for the binding affinity in chinese hamster ovary (CHO) cells transfected with human Dopamine receptor D3 using [3H]raclopride ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed