BDBM50072494 CHEMBL105814::[(S)-7-[(1H-Benzoimidazol-2-ylmethyl)-carbamoyl]-4-(2-methoxy-ethyl)-3-oxo-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-2-yl]-acetic acid

SMILES COCCN1Cc2cc(ccc2N[C@@H](CC(O)=O)C1=O)C(=O)NCc1nc2ccccc2[nH]1

InChI Key InChIKey=UJGSCIVXCHSXBE-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50072494   

TargetIntegrin alpha-V/beta-3(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072494([(S)-7-[(1H-Benzoimidazol-2-ylmethyl)-carbamoyl]-4...)
Affinity DataIC50: 3.00E+3nMAssay Description:Effect against adhesion of HEK 293 cells transfected with human alpha-v beta-3 to vitronectin coated platesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072494([(S)-7-[(1H-Benzoimidazol-2-ylmethyl)-carbamoyl]-4...)
Affinity DataKi:  28nMAssay Description:Binding affinity evaluated against vitronectin receptor (alphaV-beta3) receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed