BDBM50072402 4-[5-(4-Fluoro-phenyl)-3-(3-morpholin-4-yl-propyl)-3H-imidazol-4-yl]-pyrimidin-2-ylamine::CHEMBL274863

SMILES Nc1nccc(n1)-c1c(ncn1CCCN1CCOCC1)-c1ccc(F)cc1

InChI Key InChIKey=JDDSPCRIJZRHBB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50072402   

TargetMitogen-activated protein kinase 14(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50072402(4-[5-(4-Fluoro-phenyl)-3-(3-morpholin-4-yl-propyl)...)
Affinity DataIC50: 480nMAssay Description:Inhibitory concentration against mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50072402(4-[5-(4-Fluoro-phenyl)-3-(3-morpholin-4-yl-propyl)...)
Affinity DataIC50: 480nMAssay Description:Inhibition of p38 alpha kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11/12/13/14(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072402(4-[5-(4-Fluoro-phenyl)-3-(3-morpholin-4-yl-propyl)...)
Affinity DataIC50: 480nMAssay Description:Compound was tested for inhibition of p38 MAP kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2018
Entry Details Article
PubMed