BDBM50072130 CHEMBL3407912

SMILES OC(=O)c1cc(ncn1)-c1ccc(F)c(c1)C(F)(F)F

InChI Key InChIKey=APXXWDOJQAHCGR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50072130   

TargetKynurenine 3-monooxygenase(Human)
Evotec (Uk)

Curated by ChEMBL
LigandPNGBDBM50072130(CHEMBL3407912)
Affinity DataIC50: 32nMAssay Description:Inhibition of human KMO assessed as conversion of kynurenine to 3-hydroxykynurenine by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2016
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Human)
Evotec (Uk)

Curated by ChEMBL
LigandPNGBDBM50072130(CHEMBL3407912)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human KMO transfected in CHO cells assessed as conversion of kynurenine to 3-hydroxykynurenine by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2016
Entry Details Article
PubMed