BDBM50071191 CHEMBL2373069::actinomycin analogue

SMILES [H][C@@]12CCCN1C(=O)[C@@H](NC(=O)[C@@H](NC(=O)c1c(N)c(=O)c(C)c3oc4c(C)ccc(C(=O)N[C@H]5[C@@H](C)OC(=O)[C@H](C(C)C)N(C)C(=O)CN(C)C(=O)[C@]6([H])CCCN6C(=O)[C@@]([H])(NC5=O)[C@@H](C)CC)c4nc13)[C@@H](C)OC(=O)[C@H](C(C)C)N(C)C(=O)CN(C)C2=O)C(C)C

InChI Key InChIKey=QHPKJAQOHMCSLA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50071191   

TargetGrowth factor receptor-bound protein 2(Human)
Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL
LigandPNGBDBM50071191(actinomycin analogue | CHEMBL2373069)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of GST-Grb2 Tyrosine kinase SH2 domain binding to [3H]labeled-phosphopeptide (Ac-SpYVNK-NH-C(O)-CH2CH2H3)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed