BDBM50070442 CHEMBL263736::{(S)-1-[(S)-1-(1-Benzylcarbamoyl-4-oxo-azetidin-2-yloxymethyl)-3-methyl-butylcarbamoyl]-2,2-dimethyl-propyl}-carbamic acid tert-butyl ester

SMILES CC(C)C[C@@H](COC1CC(=O)N1C(=O)NCc1ccccc1)NC(=O)[C@@H](NC(=O)OC(C)(C)C)C(C)(C)C

InChI Key InChIKey=DYICXMIGWKPYRK-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50070442   

TargetCapsid scaffolding protein(HHV-5)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50070442({(S)-1-[(S)-1-(1-Benzylcarbamoyl-4-oxo-azetidin-2-...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibitory activity against human cytomegalovirus (HCMV) proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin B(Human)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50070442({(S)-1-[(S)-1-(1-Benzylcarbamoyl-4-oxo-azetidin-2-...)
Affinity DataIC50: 7.50E+4nMAssay Description:Inhibitory activity against Cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsin-like elastase family member 2A(Pig)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50070442({(S)-1-[(S)-1-(1-Benzylcarbamoyl-4-oxo-azetidin-2-...)
Affinity DataIC50: 7.50E+4nMAssay Description:Inhibitory activity against porcine pancreatic elastase(PPE)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50070442({(S)-1-[(S)-1-(1-Benzylcarbamoyl-4-oxo-azetidin-2-...)
Affinity DataIC50: 7.50E+4nMAssay Description:Inhibitory activity against human leukocyte elastase protease(HLE)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsinogen B(Human)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50070442({(S)-1-[(S)-1-(1-Benzylcarbamoyl-4-oxo-azetidin-2-...)
Affinity DataIC50: 8.30E+3nMAssay Description:Inhibitory activity against alpha-chymotrypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed