BDBM50070436 2-Oxo-4-(pyridin-2-ylmethylsulfanyl)-azetidine-1-carboxylic acid (2-benzyloxy-ethyl)-amide::CHEMBL36010

SMILES O=C(NCCOCc1ccccc1)N1C(CC1=O)SCc1ccccn1

InChI Key InChIKey=RBBFEHDURWQNNN-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50070436   

TargetCathepsin B(Human)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50070436(2-Oxo-4-(pyridin-2-ylmethylsulfanyl)-azetidine-1-c...)
Affinity DataIC50: 7.50E+4nMAssay Description:Inhibitory activity against Cathepsin BMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCapsid scaffolding protein(HHV-5)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50070436(2-Oxo-4-(pyridin-2-ylmethylsulfanyl)-azetidine-1-c...)
Affinity DataIC50: 6.40E+3nMAssay Description:Inhibitory activity against human cytomegalovirus (HCMV) proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetChymotrypsin-like elastase family member 2A(Pig)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50070436(2-Oxo-4-(pyridin-2-ylmethylsulfanyl)-azetidine-1-c...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibitory activity against porcine pancreatic elastase(PPE)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeutrophil elastase(Human)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50070436(2-Oxo-4-(pyridin-2-ylmethylsulfanyl)-azetidine-1-c...)
Affinity DataIC50: 7.50E+4nMAssay Description:Inhibitory activity against human leukocyte elastase protease(HLE)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetChymotrypsinogen B(Human)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50070436(2-Oxo-4-(pyridin-2-ylmethylsulfanyl)-azetidine-1-c...)
Affinity DataIC50: 7.50E+4nMAssay Description:Inhibitory activity against alpha-chymotrypsinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed