BDBM50070340 CHEMBL281025::Thiophene-2-sulfonic acid [2-(3-{[((E)-6,6-dimethyl-hept-2-en-4-ynyl)-ethyl-amino]-methyl}-phenoxy)-ethyl]-methyl-amide

SMILES CCN(C\C=C\C#CC(C)(C)C)Cc1cccc(OCCN(C)S(=O)(=O)c2cccs2)c1

InChI Key InChIKey=NEIYCJCCYGTVNA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50070340   

TargetSqualene monooxygenase(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070340(Thiophene-2-sulfonic acid [2-(3-{[((E)-6,6-dimethy...)
Affinity DataIC50: 50nMAssay Description:In vitro inhibition of pig liver squalene epoxidase in HepG2 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSqualene monooxygenase(Rat)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070340(Thiophene-2-sulfonic acid [2-(3-{[((E)-6,6-dimethy...)
Affinity DataIC50: 6.00E+3nMAssay Description:In vitro inhibition of rat liver squalene epoxidase in HepG2 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSqualene monooxygenase(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070340(Thiophene-2-sulfonic acid [2-(3-{[((E)-6,6-dimethy...)
Affinity DataIC50: 60nMAssay Description:In vitro inhibition of cholesterol biosynthesis in human HepG2 cells.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSqualene monooxygenase(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070340(Thiophene-2-sulfonic acid [2-(3-{[((E)-6,6-dimethy...)
Affinity DataIC50: 80nMAssay Description:In vitro inhibition of dog liver squalene epoxidase in HepG2 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed